Gur D, Shabason L, Borovetz H S, Herbert D L, Reece G J, Kennedy W H, Serago C
J Comput Assist Tomogr. 1981 Oct;5(5):678-83. doi: 10.1097/00004728-198110000-00015.
New developments in computed tomographic technology permit rapid, serial images that may yield information concerning tracer kinetics through a large tissue volume. One possible application of these developments is the derivation of local lung ventilation by observing the temporal changes of stable xenon concentrations. Preliminary results from six multilevel ventilation studies in dogs demonstrate that the lung may be repeatedly imaged during reproducible phases of respiration even when interscan table incrementation is employed to survey a number of tissue segments and breathing is permitted between scans. In addition, subanesthetic xenon concentrations provide adequate enhancement for possible quantification.
计算机断层扫描技术的新进展使得能够快速获取连续图像，这些图像可能会提供有关示踪剂动力学的信息，涉及较大的组织体积。这些进展的一个可能应用是通过观察稳定氙浓度的时间变化来推导局部肺通气情况。对狗进行的六项多级通气研究的初步结果表明，即使在使用扫描间床增量来扫描多个组织段且扫描之间允许呼吸的情况下，仍可在可重复的呼吸阶段对肺部进行重复成像。此外，亚麻醉氙浓度为可能的定量分析提供了足够的增强效果。
