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Species differences in responsiveness to 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene, a potent phenobarbital-like inducer of microsomal monooxygenase activity.

作者信息

Poland A, Mak I, Glover E

出版信息

Mol Pharmacol. 1981 Sep;20(2):442-50.

PMID:7300821
Abstract
摘要

相似文献

1
Species differences in responsiveness to 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene, a potent phenobarbital-like inducer of microsomal monooxygenase activity.对1,4-双[2-(3,5-二氯吡啶氧基)]苯（一种强力的类似苯巴比妥的微粒体单加氧酶活性诱导剂）反应性的种属差异。
Mol Pharmacol. 1981 Sep;20(2):442-50.
2
1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, a potent phenobarbital-like inducer of microsomal monooxygenase activity.1,4-双[2-(3,5-二氯吡啶氧基)]苯，一种强效的类似苯巴比妥的微粒体单加氧酶活性诱导剂。
Mol Pharmacol. 1980 Nov;18(3):571-80.
3
[Comparison of the inducing effect of triphenyldioxan, bis-(dichloropyridyloxy)benzene and phenobarbital on the liver monooxygenase].三苯二氧烷、双（二氯吡啶氧基）苯和苯巴比妥对肝脏单加氧酶诱导作用的比较
Biokhimiia. 1990 Jan;55(1):29-36.
4
Role of steroid hormones in hepatic microsomal enzyme induction.类固醇激素在肝微粒体酶诱导中的作用。
Biochem Pharmacol. 1971 Jul;20(7):1723-5. doi: 10.1016/0006-2952(71)90308-x.
5
Renal cortical accumulation of phenobarbital in rats and rabbits: lack of correlation with induction of renal microsomal monooxygenases.苯巴比妥在大鼠和兔子肾皮质中的蓄积：与肾微粒体单加氧酶诱导缺乏相关性。
J Pharmacol Exp Ther. 1982 Mar;220(3):547-51.
6
Strain differences in the induction of soluble and microsomal enzymes by phenobarbital and 3-methylcholanthrene.苯巴比妥和3-甲基胆蒽对可溶性酶和微粒体酶诱导作用的品系差异。
Chem Biol Interact. 1974 May;8(5):297-302. doi: 10.1016/0009-2797(74)90008-8.
7
Induction of liver microsomal mixed-function oxidases by volatile hydrocarbons.挥发性碳氢化合物对肝脏微粒体混合功能氧化酶的诱导作用。
Biochem Pharmacol. 1976 Jan;25(1):100-3. doi: 10.1016/0006-2952(76)90180-5.
8
Structure-activity relationship of bispyridyloxybenzene for induction of mouse hepatic aminopyrine N-demethylase activity. Chemical, biological, and X-ray crystallographic studies.双吡啶氧基苯诱导小鼠肝脏氨基比林N-脱甲基酶活性的构效关系。化学、生物学及X射线晶体学研究。
Mol Pharmacol. 1985 Nov;28(5):445-53.
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New potent modifiers of liver microsomal drug metabolism: 1-arylimidazoles.肝脏微粒体药物代谢的新型强效调节剂：1-芳基咪唑类化合物。
Drug Metab Dispos. 1973 Nov-Dec;1(6):775-9.
10
1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) and related compounds as inducers of hepatic monooxygenases. Structure-activity effects.1,4-双[2-(3,5-二氯吡啶氧基)]苯（TCPOBOP）及相关化合物作为肝单加氧酶诱导剂。构效关系。
Biochem Pharmacol. 1985 Oct 1;34(19):3489-94. doi: 10.1016/0006-2952(85)90722-1.

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Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT.由邻，对'-滴滴涕引发的小鼠和大鼠肝脏中PXR/CAR/ER靶基因的物种特异性调控。
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A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response.一组用于评估人孕烷X受体和组成型雄甾烷受体在药物反应中作用的新型小鼠模型。
J Clin Invest. 2008 Sep;118(9):3228-39. doi: 10.1172/JCI35483.
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1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, an extremely potent modulator of mouse hepatic cytochrome P-450 gene expression.1,4-双[2-(3,5-二氯吡啶氧基)]苯，一种对小鼠肝脏细胞色素P-450基因表达有极强调节作用的物质。
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Nonsubstrate induction of a soluble bacterial cytochrome P-450 monooxygenase by phenobarbital and its analogs.苯巴比妥及其类似物对可溶性细菌细胞色素P-450单加氧酶的非底物诱导作用。
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Genetic susceptibility to murine hepatocarcinogenesis is associated with high growth rate of NDEA-initiated hepatocytes.小鼠肝癌发生的遗传易感性与经NDEA启动的肝细胞的高生长率相关。
J Cancer Res Clin Oncol. 1987;113(3):223-9. doi: 10.1007/BF00396377.