丁酸梭菌引起的坏死性小肠结肠炎暴发

Outbreak of necrotising enterocolitis caused by Clostridium butyricum.

作者信息

Howard F M, Flynn D M, Bradley J M, Noone P, Szawatkowski M

出版信息

Lancet. 1977 Nov 26;2(8048):1099-1102. doi: 10.1016/s0140-6736(77)90546-3.

Abstract

12 hospital-born babies had necrotising enterocolitis, of varying severity, within six weeks, 5 of them within ten days. The usually described predisposing causes were absent in most, though no baby was exclusively breast -fed. Evidence of the presence of Clostridium butyricum was found in the blood of 9 out of 10 babies examined. Cl. butyricum is probably a primary, not a secondary invader.

摘要

12名在医院出生的婴儿在六周内出现了不同严重程度的坏死性小肠结肠炎，其中5名在十天内发病。大多数婴儿不存在通常所说的诱发因素，不过没有婴儿是完全母乳喂养的。在接受检查的10名婴儿中，有9名婴儿的血液中发现了丁酸梭菌存在的证据。丁酸梭菌可能是原发性入侵者，而非继发性入侵者。