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35岁及以上黑人女性的妊娠结局。

Pregnancy outcomes in black women aged 35 and older.

作者信息

Grimes D A, Gross G K

出版信息

Obstet Gynecol. 1981 Nov;58(5):614-20.

PMID:7301238
Abstract

Pregnancy outcomes of women 35 years of age or older are considered to be less favorable than those of younger women. To examine this hypothesis, the records of 26,795 deliveries of black women at Grady Memorial Hospital from 1973 to 1978 were analyzed. Infants of 788 women who were 35 or older had a perinatal mortality rate 1.7 times higher than did infants of younger women (47 versus 28 deaths per 1000 births; P less than .01). There was no difference, however, when women with preexisting hypertension were excluded from analysis. The incidence of primary cesarean section was significantly higher for women 46 or older (17% versus 10%; P less than .001), although incidences of infants with low birth weight, low Apgar scores, and maternal infections were not significantly different. Hypertension was a more important determinant of perinatal survival than was maternal age. Age alone did not appear to be an important obstetric risk factor for healthy women 35 years of age or older.

摘要

35岁及以上女性的妊娠结局被认为不如年轻女性的妊娠结局。为了检验这一假设,对1973年至1978年在格雷迪纪念医院分娩的26795名黑人女性的记录进行了分析。788名35岁及以上女性的婴儿围产期死亡率比年轻女性的婴儿高1.7倍(每1000例出生中有47例死亡,而年轻女性为28例死亡;P小于0.01)。然而,当排除已有高血压的女性进行分析时,差异并不存在。46岁及以上女性的初次剖宫产发生率显著更高(17%对10%;P小于0.001),尽管低出生体重婴儿发生率、低阿氏评分婴儿发生率和产妇感染发生率并无显著差异。高血压对围产期生存的决定作用比产妇年龄更为重要。对于35岁及以上的健康女性而言,年龄本身似乎并非重要的产科危险因素。

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