Haines C J, Rogers M S, Leung D H
Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
Aust N Z J Obstet Gynaecol. 1991 Aug;31(3):209-12. doi: 10.1111/j.1479-828x.1991.tb02782.x.
The relationship between maternal age and neonatal outcome was examined in 22,689 pregnancies using various determinants of neonatal well-being which included evidence of fetal distress, birth-weight, Apgar scores, the necessity for admission to the neonatal unit and other indicators of neonatal morbidity. Differences in the incidence of congenital malformations and perinatal mortality were also studied. There was a trend towards more frequent fetal heart monitoring, lower birth-weight and a higher rate of neonatal unit admission for infants delivered by younger women. There was also a significant increase in the Caesarean section rate with advancing maternal age. Maternal age had no effect, however, on the incidence of fetal distress, Apgar score, the development of respiratory disease, the need for intubation and ventilation nor on subsequent neonatal central nervous system complications. There was also no association between maternal age and either perinatal mortality or the incidence of congenital malformations. The favourable outcome in teenagers in this study may have been influenced by the extremely low pregnancy rate amongst young adolescents in Hong Kong, but a similar outcome in the mature age women was likely to have reflected the recognition of risk and its appropriate management.
在22689例妊娠中，研究了母亲年龄与新生儿结局之间的关系，采用了多种新生儿健康决定因素，包括胎儿窘迫证据、出生体重、阿氏评分、入住新生儿病房的必要性以及其他新生儿发病指标。还研究了先天性畸形发病率和围产期死亡率的差异。年轻女性分娩的婴儿有更频繁进行胎儿心脏监测、出生体重较低和入住新生儿病房率较高的趋势。随着母亲年龄的增长，剖宫产率也显著增加。然而，母亲年龄对胎儿窘迫发生率、阿氏评分、呼吸系统疾病的发展、插管和通气的需求以及随后的新生儿中枢神经系统并发症均无影响。母亲年龄与围产期死亡率或先天性畸形发生率之间也没有关联。本研究中青少年的良好结局可能受到香港青少年极低妊娠率的影响，但成熟年龄女性的类似结局可能反映了对风险的认识及其适当管理。
