Bloustein P A
Hum Pathol. 1978 Nov;9(6):713-5. doi: 10.1016/s0046-8177(78)80054-9.
A primary leiomyosarcoma of the liver in a 12 year old female is reported. It is the eleventh such tumor to be recorded, the first to be documented in an adolescent and the first to be studied electron microscopically. By light microscopy the well differentiated portions of the tumor were characteristic of leiomyosarcoma. Ultrastructurally a minority of tumor cells contained myofilaments along with cytoplasmic dense bodies and marginal dense plaques, the most distinctive subcellular markers of smooth muscle cells. A brief review of the differential diagnosis is provided.
报告了一例12岁女性原发性肝平滑肌肉瘤。这是有记录的第11例此类肿瘤，首例记录于青少年患者，也是首例进行电子显微镜研究的病例。光镜下，肿瘤的高分化部分具有平滑肌肉瘤的特征。超微结构显示，少数肿瘤细胞含有肌丝以及胞质致密小体和边缘致密斑，这是平滑肌细胞最具特征性的亚细胞标志物。本文还提供了鉴别诊断的简要综述。
