不明原因发热。下丘脑垂体功能减退的表现体征。
Pyrexia of unknown origin. Presenting sign of hypothalamic hypopituitarism.
作者信息
Marilus R, Barkan A, Leiba S, Arie R, Blum I
出版信息
Postgrad Med J. 1981 May;57(667):310-3. doi: 10.1136/pgmj.57.667.310.
Abstract
A 62-year-old man was admitted to hospital 10 times over 12 years because of pyrexia of unknown origin. Hypothalamic hypopituitarism was diagnosed by dynamic tests including clomiphene, LRH, TRH and chlorpromazine stimulation. Lack of ACTH was demonstrated by long and short tetracosactrin tests. The aetiology of the disorder was believed to be previous encephalitis. Following substitution therapy with adrenal and gonadal steroids there were no further episodes of fever.
摘要
一名62岁男性在12年间因不明原因发热入院10次。通过克罗米芬、促黄体生成素释放激素、促甲状腺激素释放激素和氯丙嗪刺激等动态试验诊断为下丘脑垂体功能减退。长短程促肾上腺皮质激素试验证实促肾上腺皮质激素缺乏。该疾病的病因被认为是既往脑炎。在使用肾上腺和性腺类固醇进行替代治疗后，未再出现发热发作。
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