Neville E, Graham P Y, Brewis R A
Postgrad Med J. 1981 Jun;57(668):378-9. doi: 10.1136/pgmj.57.668.378.
The case is reported of a man developing drug-induced systemic lupus erythematosus while taking hydralazine. The illness was characterized by arthritis and a purpuric rash particularly in the light-sensitive areas as well as orogenital and cutaneous ulceration. Anti-nuclear antibody and DNA binding were positive. All clinical manifestations disappeared on withdrawal of hydralazine.
报告了一例服用肼苯哒嗪后发生药物性系统性红斑狼疮的男性病例。该疾病的特征为关节炎、尤其是在光敏部位出现紫癜性皮疹以及口腔生殖器和皮肤溃疡。抗核抗体和DNA结合试验呈阳性。停用肼苯哒嗪后所有临床表现均消失。
