先天性甲状腺功能减退症中终末器官对甲状腺激素的部分抵抗
Partial end organ resistance to thyroid hormone in congenital hypothyroidism.
作者信息
Connell J M, McLaren E H
出版信息
Postgrad Med J. 1981 Aug;57(670):518-20. doi: 10.1136/pgmj.57.670.518.
Abstract
End organ resistance to thyroid hormone has been described for a number of years: the defect may be partial or generalized. A case of partial end organ resistance to thyroid hormone in congenital hypothyroidism is described, with evidence of an alteration in TSH threshold to feedback inhibition by thyroid hormone. The implications of this factor in the management of hypothyroidism are discussed.
摘要
终末器官对甲状腺激素的抵抗已被描述多年
这种缺陷可能是部分性的或全身性的。本文描述了一例先天性甲状腺功能减退症中部分终末器官对甲状腺激素抵抗的病例，有证据表明促甲状腺激素（TSH）对甲状腺激素反馈抑制的阈值发生了改变。本文讨论了该因素在甲状腺功能减退症管理中的意义。
相似文献
1
Partial end organ resistance to thyroid hormone in congenital hypothyroidism.先天性甲状腺功能减退症中终末器官对甲状腺激素的部分抵抗
Postgrad Med J. 1981 Aug;57(670):518-20. doi: 10.1136/pgmj.57.670.518.
2
Serum thyroxine and thyroid stimulating hormone concentrations after treatment of congenital hypothyroidism.先天性甲状腺功能减退症治疗后的血清甲状腺素和促甲状腺激素浓度
Arch Dis Child. 1988 Nov;63(11):1368-71. doi: 10.1136/adc.63.11.1368.
3
Congenital hypothyroidism.
Pediatr Nurs. 1984 Sep-Oct;10(5):342-5.
4
Hypothyroidism.甲状腺功能减退症
Pediatr Rev. 2014 Aug;35(8):336-47; quiz 348-9. doi: 10.1542/pir.35-8-336.
5
[Congenital hypothyroidism in the first 2 years of life. Development of biological parameters and therapeutic recommendations].
Ann Pediatr (Paris). 1986 Apr;33(4):291-5.
6
Microfollicular thyroid adenoma and congenital goitrous hypothyroidism.微滤泡性甲状腺腺瘤与先天性甲状腺肿性甲状腺功能减退症
Arch Dis Child. 1992 Oct;67(10):1294-5. doi: 10.1136/adc.67.10.1294.
7
Pseudotumor cerebri in an infant after L-thyroxine therapy for transient neonatal hypothyroidism.左旋甲状腺素治疗短暂性新生儿甲状腺功能减退症后婴儿出现的假性脑瘤
J Pediatr. 1997 Mar;130(3):478-80. doi: 10.1016/s0022-3476(97)70215-4.
8
Factors involved in the rate of fall of thyroid stimulating hormone in treated hypothyroidism.治疗后甲状腺功能减退症中促甲状腺激素下降速率的相关因素。
Arch Dis Child. 1997 Dec;77(6):526-7. doi: 10.1136/adc.77.6.526.
9
10
Congenital hypothyroidism and mental development.
Compr Ther. 1994;20(6):342-6.
本文引用的文献
1
Elevated threshold for thyrotropin suppression in congenital hypothyroidism.先天性甲状腺功能减退症中促甲状腺激素抑制的阈值升高。
Am J Dis Child. 1980 Jan;134(1):19-20. doi: 10.1001/archpedi.1980.02130130011004.
2
The short cardiac pre-ejection period: an index to thyrotoxicosis.心脏射血前期缩短：甲状腺毒症的一项指标。
Circulation. 1974 May;49(5):900-4. doi: 10.1161/01.cir.49.5.900.
3
Partial target organ resistance to thyroid hormone.部分靶器官对甲状腺激素抵抗。
J Clin Invest. 1973 Apr;52(4):776-82. doi: 10.1172/JCI107240.
4
Thyrotropin-induced hyperthyroidism caused by selective pituitary resistance to thyroid hormone. A new syndrome of "inappropriate secretion of TSH".由选择性垂体对甲状腺激素抵抗引起的促甲状腺素诱导的甲状腺功能亢进症。一种“促甲状腺素分泌不当”的新综合征。
J Clin Invest. 1975 Sep;56(3):633-42. doi: 10.1172/JCI108133.
5
Reassessment of the daily dose of oral thyroxine for replacement therapy in hypothyroid children.
J Pediatr. 1977 Feb;90(2):291-7. doi: 10.1016/s0022-3476(77)80655-0.
6
Age-related change in pituitary threshold for TSH release during thyroxine replacement therapy for cretinism.克汀病甲状腺素替代治疗期间垂体促甲状腺激素释放阈值的年龄相关变化。
J Clin Endocrinol Metab. 1977 Mar;44(3):553-9. doi: 10.1210/jcem-44-3-553.
Zotero 插件