Vandevenne A, Moyses B, Weitzenblum E, Carloz I, Methlin G
Poumon Coeur. 1981;37(3):223-8.
The regional distribution of ventilation (Vr), perfusion (Qr) (expressed in absolute values) and the regional distribution of ventilated lung volume, of ventilation and of perfusion (expressed as %) were studied using Xenon 133 in 13 subjects with a unilateral pleural effusion of proven or presumed tuberculous origin. The examinations were performed in a sitting position. The initial examination was carried out after as complete an evacuation as possible of the fluid effusion. Eight subjects underwent a follow-up examination after two months treatment with tuberculostatic agents combined with daily respiratory physiotherapy. The initial results emphasized the following points: - in absolute values, a deficit in ventilation on the involved side affecting the 3 regions explored without any similar change in perfusion ; a hyperventilation on the controlateral upper and middle regions ; - in relative values, a slight deficit in ventilated volume and perfusion localised at the base, whilst the deficit in ventilation was more marked and more extensive. After treatment the contribution to ventilation of the involved side increased on average by 6%. However this improvement only concerned the lower territory. The mechanisms of impairment of regional function and its improvement under the influence of treatment are discussed.
运用氙133对13例经证实或推测为结核性起源的单侧胸腔积液患者进行研究，观察通气（Vr）、灌注（Qr）的区域分布（以绝对值表示）以及通气肺容积、通气和灌注的区域分布（以百分比表示）。检查在坐位进行。首次检查在尽可能完全抽吸出胸腔积液后进行。8例患者在接受抗结核药物联合每日呼吸物理治疗两个月后接受了随访检查。初始结果强调了以下几点：- 以绝对值计，患侧通气不足，累及所探查的3个区域，而灌注无类似变化；对侧上中部区域通气过度；- 以相对值计，通气量和灌注在底部略有不足，而通气不足更为明显且范围更广。治疗后，患侧对通气的贡献平均增加了6%。然而，这种改善仅涉及下部区域。文中讨论了区域功能受损的机制及其在治疗影响下的改善情况。
