Gillespie D J, Rehder K
Division of Thoracic Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Intensive Care Med. 1989;15(4):266-8. doi: 10.1007/BF00271064.
The effect of pleural effusion on lung function and gas exchange has not been adequately defined. We used the multiple "inert" gas technique to study gas exchange and ventilation-perfusion relationships in both the left and the right lateral decubitus positions in a patient with a moderate unilateral (left) pleural effusion. With position change, only a small change in oxygenation (3 mm Hg) and no change in carbon dioxide tension occurred. The ventilation-perfusion relationships were also nearly identical for both body positions. We conclude that a pleural effusion of moderate size has little effect on overall gas exchange and ventilation-perfusion relationships and that complex mechanisms of the respiratory system compensate for the effusion.
胸腔积液对肺功能和气体交换的影响尚未得到充分明确。我们采用多种“惰性”气体技术，对一名患有中度单侧（左侧）胸腔积液的患者在左侧卧位和右侧卧位时的气体交换及通气-灌注关系进行了研究。随着体位改变，氧合仅有微小变化（3毫米汞柱），二氧化碳分压未发生改变。两种体位下的通气-灌注关系也几乎相同。我们得出结论，中等量的胸腔积液对整体气体交换和通气-灌注关系影响很小，呼吸系统的复杂机制可代偿这种积液。
