Delwaide P J, Mesraoua B, De Pasqua V
Rev Electroencephalogr Neurophysiol Clin. 1980 Oct-Dec;10(4):338-42. doi: 10.1016/s0370-4475(80)80031-1.
Visual evoked potentials were studied in 23 patients with Parkinson's disease at varying stages, and in 23 normal subjects of the same age. The latency of the P wave is increased in the Parkinson group in a significant manner and becomes more marked as the disease progresses. The difference in latency between the potentials evoked by stimuli applied to both eyes is also significantly increased in Parkinson's disease. The interpretation of these results remains obscure, but "peripheral" retinal and "central" mechanisms are probably involved. From a practical point of view, these results demonstrate that increases in latency of visual evoked potentials are not always due to localized demyelinization. Study of visual evoked potentials could be of values when investigating patients with Parkinson's disease.
对23例处于不同阶段的帕金森病患者以及23名同龄正常受试者进行了视觉诱发电位研究。帕金森病组P波潜伏期显著延长,且随着疾病进展变得更加明显。帕金森病患者双眼受刺激诱发的电位潜伏期差异也显著增大。这些结果的解释仍不明确,但可能涉及“外周”视网膜和“中枢”机制。从实际角度来看,这些结果表明视觉诱发电位潜伏期延长并不总是由于局限性脱髓鞘所致。在对帕金森病患者进行调查时,视觉诱发电位研究可能具有价值。