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Report on a double-blind trial comparing small and large doses of gold in the treatment of rheumatoid disease.

作者信息

McKenzie J M

出版信息

Rheumatol Rehabil. 1981 Nov;20(4):198-202. doi: 10.1093/rheumatology/20.4.198.

DOI:10.1093/rheumatology/20.4.198
PMID:7302464
Abstract

A double-blind trial was carried out for one year on 60 patients suffering from rheumatoid disease. A dosage of 10 mg of sodium aurothiomalate weekly was compared to 50 my weekly. The method and regime of the trial are described. Analysis of the results showed no statistical difference in response between the two groups. There was no appreciable difference in the toxic effects between the two groups and those reported were not serious.

摘要

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引用本文的文献

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Clinical pharmacokinetics of slow-acting antirheumatic drugs.慢作用抗风湿药物的临床药代动力学
Clin Pharmacokinet. 1993 Nov;25(5):392-407. doi: 10.2165/00003088-199325050-00005.
2
Oral gold for rheumatoid arthritis.用于类风湿性关节炎的口服金制剂
Br Med J (Clin Res Ed). 1984 Oct 6;289(6449):858-9. doi: 10.1136/bmj.289.6449.858.