Ying Q L, Liang Z Q, Wu H, Wang L F
Sci Sin. 1981 Nov;24(11):1597-602.
By screening a Chinese population of 1025 unrelated persons in Beijing, three serum albumin variants were discovered, and the gene frequency of serum albumin variants of Chinese is estimated as 0.0015. These albumin variants can be distinguished electrophoretically from each other, and were named tentatively as albumin Hanzhong, albumin Changzhi and albumin LXX respectively. A polyacrylamide gel electrophoresis procedure has been developed to characterize albumin variants by determining the relative mobilities (Rm) of albumin variants in a tris-succinate buffer system.
通过对北京1025名无亲缘关系的中国人进行筛查,发现了三种血清白蛋白变体,中国人群血清白蛋白变体的基因频率估计为0.0015。这些白蛋白变体可通过电泳相互区分,分别暂命名为汉中白蛋白、长治白蛋白和LXX白蛋白。已开发出一种聚丙烯酰胺凝胶电泳程序,通过测定白蛋白变体在三羟甲基氨基甲烷 - 琥珀酸盐缓冲系统中的相对迁移率(Rm)来表征白蛋白变体。