Sortwell R J, Dawe S, Allen D G, Street A E, Heywood R, Edmondson N A, Gopinath C
Toxicol Lett. 1981 Sep;9(1):81-5. doi: 10.1016/0378-4274(81)90179-x.
The prolonged effects of overdosage with lentinan in the rhesus monkey are associated with foam cell reactions in lung, liver, kidney, spleen, lymph nodes and bone marrow and with varying degrees of vasculitis and associated reactions. A dose level of 0.5 mg/kg/day was without adverse effect.