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60Coγ射线治疗癌症患者时免疫球蛋白、循环免疫复合物和血浆游离血红蛋白的研究

Investigation of immunoglobulins, circulating immune complexes and plasma free hemoglobin in cancer patients on 60Co gamma-ray therapy.

作者信息

Horváth M, Rodé I L, Fekete B, Kiss B, Ringwald G

出版信息

Strahlentherapie. 1981 Oct;157(10):673-6.

PMID:7303023
Abstract

32 patients with different tumours were irradiated by 60Co gamma-rays. During therapy lasting for several weeks, changes in the content of immunoglobulin and of some other serum proteins, circulating immune complexes and plasma free hemoglobin were determined. Immunosuppression according to immunoglobulin content in serum was not produced by this type of radiation. Decrease in immune complex levels was a good prognostic sign. Low values of plasma hemoglobin content during treatment indicated that no erythrocyte membrane damage had been effected.

摘要

32名患有不同肿瘤的患者接受了60钴γ射线照射。在持续数周的治疗期间,测定了免疫球蛋白及其他一些血清蛋白的含量、循环免疫复合物和血浆游离血红蛋白的变化。这种类型的辐射并未根据血清中免疫球蛋白含量产生免疫抑制作用。免疫复合物水平的降低是一个良好的预后指标。治疗期间血浆血红蛋白含量较低表明未发生红细胞膜损伤。

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