Rodrigues F M, Guttikar S N, Pinto B D
Trans R Soc Trop Med Hyg. 1981;75(2):258-62. doi: 10.1016/0035-9203(81)90330-8.
In the Krishna-Godavari Delta region of the State of Andhra Pradesh, India, 866 sera obtained from trapped birds of 13 species were tested for neutralizing antibody to Japanese encephalitis (JE) virus; two species of birds belonging to the family Ardeidae, Ardeola grayii (pond heron) and Bubulcus ibis (cattle egret), contributed 514 of these sera. Neutralizing antibody to JE virus--i.e. sera giving positive reactions--was detected in 179 sera (34.8%) from these two species; in addition, two sera (0.4%) gave equivocal reactions, presumably indicating partial protection. There were only nine positive reactors (2.6%) among the remaining 352 sera from all other bird species. Of the 181 sera from ardeid birds in which neutralizing activity was detected, 174 were tested for neutralizing antibody to West Nile (WN) virus. The results indicated that 35.6% of these 179 sera had antibody specific to JE virus only and 63.8% possessed neutralizing antibodies to JE virus or to WN virus or to both; these figures represent 12.5% and 22.5% , respectively, of the total of 514 birds of these two species which were tested for neutralizing antibody to JE virus. The findings suggest that ardeid birds may be involved in the natural cycle of JE virus and, possibly, also of WN virus in India.
在印度安得拉邦的克里希纳-戈达瓦里三角洲地区，对从13种被困鸟类身上采集的866份血清进行了检测，以确定其对日本脑炎（JE）病毒的中和抗体；鹭科的两种鸟类，即苍鹭（池鹭）和牛背鹭，提供了其中的514份血清。在这两种鸟类的179份血清（34.8%）中检测到了对JE病毒的中和抗体，即呈阳性反应的血清；此外，两份血清（0.4%）反应不明确，可能表明有部分保护作用。在来自所有其他鸟类的其余352份血清中，只有9份呈阳性反应（2.6%）。在检测到中和活性的181份鹭科鸟类血清中，有174份检测了对西尼罗河（WN）病毒的中和抗体。结果表明，这179份血清中35.6%仅具有针对JE病毒的抗体，63.8%具有针对JE病毒或WN病毒或两者的中和抗体；这些数字分别占这两种接受JE病毒中和抗体检测的514只鸟类总数的12.5%和22.5%。这些发现表明，鹭科鸟类可能参与了印度JE病毒以及可能还有WN病毒的自然循环。
