Mihail A, Popa L M, Petrescu A, Dumitrescu S M
Virologie. 1981 Jul-Sep;32(3):225-9.
Simultaneous inoculation of chick embryos with a standard laboratory influenza virus--A/PR8/34 (H0N1)--and with an autochthonous epidemic strain--belonging to the antigenic subtype A(H1N1) of A(H3N2), respectively--resulted in the isolation of two genetic recombinants, designated R1IVN (H1N1) and R2IVN (H3N2). Each recombinant was antigenically identical to its wild-type parent and exhibited a hemagglutinating titer in chick embryos about 4-fold greater than that of the autochthonous parental strain.
将标准实验室流感病毒——A/PR8/34（H0N1）——与一株本地流行毒株——分别属于A（H3N2）的A（H1N1）抗原亚型——同时接种到鸡胚中，结果分离出两种基因重组体，分别命名为R1IVN（H1N1）和R2IVN（H3N2）。每种重组体在抗原性上与其野生型亲本相同，并且在鸡胚中的血凝滴度比本地亲本毒株高约4倍。
