Ulrich F E, Frahnert C, Frahnert W
Z Gesamte Inn Med. 1981 Oct 1;36(19):690-6.
10% of the inhabitants of the district of Naumburg were examined for their state of the thyroid gland. The average morbidity of struma was 25.2%. Above all the struma stages I and II were found. The maxima of frequency were in the age groups of the 20--29-year-old persons with 68% in the females and 27.4% in the males. Of the 585 inhabitants of the village Grossjena (85% of the total population) 32.9% has a struma. The patterns of distribution corresponded, apart from a second peak in the females at the time of the climacterium, to the patterns found in the whole region of Naumburg. The average iodine excretion in the urine of 19.9 micrograms/g creatinine was still undercut by the 12- to 15-year-old pupils of this village with 14.8 micrograms/g creatinine. The relation of female to male carriers of struma was on an average at 2.5 : 1. In individual age groups the sex-conditioned differences were eliminated. Relation of sex, excretion of iodine and frequency of struma confirm the endemic character of the struma disease in the district of Naumburg and confirm an iodine deficiency of IInd to IIIrd degree. The results intensely emphasize the necessity of a centrally regulated iodate prophylaxis.
瑙姆堡区10%的居民接受了甲状腺状况检查。甲状腺肿的平均发病率为25.2%。主要发现的是I期和II期甲状腺肿。发病频率最高的年龄段为20至29岁人群,其中女性为68%,男性为27.4%。在大耶纳村的585名居民(占总人口的85%)中,32.9%患有甲状腺肿。除了女性在更年期时出现第二个峰值外,分布模式与瑙姆堡整个地区的模式相符。这个村庄12至15岁的学生尿碘排泄平均为14.8微克/克肌酐,仍低于19.9微克/克肌酐的平均水平。甲状腺肿女性携带者与男性携带者的比例平均为2.5:1。在个别年龄组中,性别差异消失。性别、碘排泄和甲状腺肿发病率的关系证实了瑙姆堡区甲状腺肿疾病的地方性特征,并证实存在II至III度碘缺乏。结果强烈强调了集中控制碘酸盐预防措施的必要性。