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[不同致病性葡萄球菌的比较免疫化学和免疫变态反应特征。II. 金黄色葡萄球菌和表皮葡萄球菌提取物在迟发型变态反应中的诊断价值]

[Comparative immunochemical and immunoallergic characteristics of staphylococci of different pathogenicity. II. Diagnostic value of extracts of Staphylococcus aureus and Staphylococcus epidermidis in delayed type allergic reactions].

作者信息

Darkanbaeva E T, Sukhodoeva G S, Bul'vakhter Ia L, Shuratova S G, Koval' G P

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1981 Sep(9):42-6.

PMID:7304031
Abstract

A total of 20 different allergens extracted from various staphylococcal strains were studied in the delayed hypersensitivity reactions in experiments on guinea-pigs. The most intensive dermatoallergic reactions were observed after the injection of the cytoplasmic fraction, acidic and alkaline extracts; reactions to the allergen of Ando-Verzhikovsky were less pronounced. The cytoplasmic fraction and the allergen of ando-Verzhikovsky were more active in the reaction of leukocyte migration inhibition in the blood. Both common and individual allergenic components were detected. No correlation between the results of the immunochemical and allergological studies of staphylococcal extracts was revealed.

摘要

在豚鼠实验中,对从各种葡萄球菌菌株中提取的总共20种不同过敏原进行了迟发型超敏反应研究。注射细胞质部分、酸性和碱性提取物后观察到最强烈的皮肤过敏反应;对安藤-韦尔日科夫斯基过敏原的反应不太明显。细胞质部分和安藤-韦尔日科夫斯基过敏原在血液白细胞迁移抑制反应中更具活性。检测到了共同的和个体的过敏原成分。未发现葡萄球菌提取物的免疫化学和变应性研究结果之间存在相关性。

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