Feely J
Acta Endocrinol (Copenh). 1981 Dec;98(4):528-32. doi: 10.1530/acta.0.0980528.
The effect of propranolol on serum calcium was studied in 25 patients with thyrotoxicosis including 5 with hypercalcemia. In patients with hypercalcaemia iv propranolol significantly reduced serum calcium. Oral therapy 160 mg/day reduced calcium non-significantly from 2.72 +/- 0.09 (mean +/- SD) to 2.59 +/- 0.13 mmol/l, however on 320 mg/day the reduction (to 2.5 +/- 0.15 mmol/l) was significant. In normocalcaemic patients oral propranolol did not influence serum calcium. Both in hyper- and normocalcemic thyrotoxic patients propranolol increased (P less than 0.01) serum phosphate.
对25例甲状腺毒症患者（其中5例伴有高钙血症）研究了普萘洛尔对血清钙的影响。在高钙血症患者中，静脉注射普萘洛尔可显著降低血清钙。口服疗法，每日160毫克，可使血钙从2.72±0.09（均值±标准差）毫摩尔/升降至2.59±0.13毫摩尔/升，降幅不显著，然而每日320毫克时，血钙降至2.5±0.15毫摩尔/升，降幅显著。在血钙正常的患者中，口服普萘洛尔不影响血清钙。在甲状腺毒症伴高钙血症和血钙正常的患者中，普萘洛尔均可使血清磷酸盐升高（P＜0.01）。
