自身免疫性血小板减少症中的补体结合血小板自身抗体
Complement-fixing platelet autoantibodies in autoimmune thrombocytopenia.
作者信息
Kayser W, Meuller-Eckhardt C, Budde U, Schmidt R E
出版信息
Am J Hematol. 1981 Sep;11(2):213-9. doi: 10.1002/ajh.2830110213.
A 16-year-old male patient is described with chronic autoimmune thrombocytopenic purpura and, after two years, "warm" autoimmune hemolytic anemia (Evans syndrome) who transiently developed complement-fixing platelet autoantibodies. The autoreactivity of these antibodies was established by quantitative complement fixation as well as by absorption and elution studies using autologous platelets. We believe this to be the first documented case with this very rare and peculiar type of platelet autoantibody.
本文描述了一名16岁男性患者，患有慢性自身免疫性血小板减少性紫癜，两年后又出现“温抗体型”自身免疫性溶血性贫血（伊文氏综合征），该患者短暂产生了补体结合性血小板自身抗体。这些抗体的自身反应性通过定量补体结合试验以及使用自体血小板的吸收和洗脱研究得以确定。我们认为这是首例记录在案的这种极为罕见且特殊类型的血小板自身抗体病例。
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