Boyle P C, Storlien L H, Harper A E, Keesey R E
Am J Physiol. 1981 Nov;241(5):R392-7. doi: 10.1152/ajpregu.1981.241.5.R392.
Both the resting rate of O2 consumption and the heat increment in response to an intubated meal were measured in male rats following periods of food restriction and during realimentation. In one experiment, resting rates of O2 consumption were significantly reduced below control values after food consumption had been restricted and during a substantial part of an 11-day period of controlled realimentation. In a second experiment, the heat increment in response to an intubated meal was also significantly less following an interval of food restriction and during the early stages of realimentation. The reduction in O2 consumption was not related to reduced locomotor activity. These results obtained whether O2 consumption was measured in absolute amount or was referenced to an estimate of the animal's metabolically active tissue (kg body wt0.75). It is suggested that these metabolic adaptations contribute significantly to the enhanced efficiency of food utilization reported in food-restricted animals during controlled realimentation.
在雄性大鼠经历食物限制期及再喂养期间，测量了其静息状态下的耗氧率以及对经插管喂食的热增量。在一项实验中，在食物摄入受限后以及为期11天的受控再喂养的大部分时间里，静息耗氧率显著低于对照值。在第二项实验中，在食物限制期及再喂养早期，对经插管喂食的热增量也显著降低。耗氧量的减少与运动活动减少无关。无论耗氧量是以绝对量测量还是参照动物代谢活跃组织（千克体重0.75）的估计值来计算，均得到这些结果。提示这些代谢适应性变化对食物限制动物在受控再喂养期间所报道的食物利用效率提高有显著贡献。
