Sheng H P, Huggins R A, Garza C, Evans H J, LeBlanc A D, Nichols B L, Johnson P C
Am J Physiol. 1981 Nov;241(5):R419-22. doi: 10.1152/ajpregu.1981.241.5.R419.
Body sodium (Na), calcium (Ca), and chloride (Cl) of guinea pigs weighing between 227 and 600 g were measured by total body neutron activation analysis (TBNAA) followed by chemical analysis (CA) on 12-17 animals. Paired t test was used to compare any differences in the results obtained by the two methods. There was no significant difference in the results for the three elements. The means and standard deviation for Ca (g/100 g body wt) 1.070 +/- 0.132 (TBNAA) and 1.107 +/- 0.125 (CA); for Na 0.149 +/- 0.019 (TBNAA) and 0.143 +/- 0.021 (CA); and for Cl 0.126 +/- 0.009 (TBNAA) and 0.132 +/- 0.024 (CA). Neutron activation analysis alone, in a series of 27 animals, gave means (g/100 g body wt) and standard deviation of 1.110 +/- 0.084 for Ca, 0.120 +/- 0.009 for Cl, and 0.153 +/- 0.011 for Na. TBNAA has potential usefulness, particularly in longitudinal studies in the same animal, because of its accuracy and the rapidity and ease with which the measurements can be made.
对体重在227至600克之间的豚鼠，通过全身中子活化分析（TBNAA）测量其体内的钠（Na）、钙（Ca）和氯（Cl）含量，随后对12 - 17只动物进行化学分析（CA）。采用配对t检验比较两种方法所得结果的差异。三种元素的结果无显著差异。钙（克/100克体重）的均值和标准差分别为：1.070±0.132（TBNAA）和1.107±0.125（CA）；钠为0.149±0.019（TBNAA）和0.143±0.021（CA）；氯为0.126±0.009（TBNAA）和0.132±0.024（CA）。在一系列27只动物中，仅进行中子活化分析时，钙的均值（克/100克体重）和标准差为1.110±0.084，氯为0.120±0.009，钠为0.153±0.011。由于其准确性以及测量的快速性和简便性，全身中子活化分析具有潜在的实用性，尤其适用于对同一动物的纵向研究。
