Engler R
Ann Biol Clin (Paris). 1981;39(4):193-6.
Simultaneous assay of haptoglobulin, hemopexin and orosomucoid allowed detection and quantification of intravascular hemolysis with or without inflammatory reactions. In cases of intravascular or extravascular hemolysis, the concentration of plasma haptoglobulin is greatly diminished, this generally being accompanied by an increase in free bilirubin. This last characteristic allows differentiation from intravascular hemolysis where the free bilirubin concentration remain normal.
同时检测触珠蛋白、血红素结合蛋白和血清类黏蛋白,能够检测和定量有无炎症反应情况下的血管内溶血。在血管内或血管外溶血的情况下,血浆触珠蛋白浓度会大幅降低,通常还伴有游离胆红素增加。这最后一个特征有助于与游离胆红素浓度保持正常的血管内溶血相鉴别。