Hume A L, Cant B R
Ann Neurol. 1981 Nov;10(5):411-9. doi: 10.1002/ana.410100503.
In 94 patients with head injuries, conduction between the lower brainstem and the cerebral cortex was studied by recording evoked potentials from the scalp and neck following stimulation of the median nerves. A conduction time 3 SD or more above the normal mean (5.74 +/- 0.46 msec) or the absence of an evoked potential over one or both hemispheres was considered abnormal. During successive periods in the first 35 days after injury, the evoked potentials correlated with the outcome (classified as good or not good) in 75 to 84% of patients. Within 3 1/2 days the outcome was correctly predicted in 38 of 49 patients (78%). Six of the 7 surviving patients with persistent asymmetries of the cerebral evoked potentials remained hemiplegic. Serial studies over one year showed that both conduction time and amplitude recovered exponentially over many months, but differences persisted between the patients who made a good recovery and those who remained disabled.
在94例头部受伤患者中，通过刺激正中神经后记录头皮和颈部的诱发电位，研究了低位脑干与大脑皮层之间的传导情况。传导时间比正常均值（5.74±0.46毫秒）高出3个标准差或更多，或者一个或两个半球未引出诱发电位，均被视为异常。在受伤后的前35天内，连续各时段诱发电位与患者预后（分为良好或不佳）的相关性在75%至84%之间。在3.5天内，49例患者中有38例（78%）的预后得到了正确预测。7例存活的大脑诱发电位持续不对称的患者中有6例仍为偏瘫。为期一年的系列研究表明，传导时间和波幅在数月内均呈指数恢复，但恢复良好的患者与仍有残疾的患者之间仍存在差异。
