Tan K L
Arch Dis Child. 1981 Nov;56(11):874-7. doi: 10.1136/adc.56.11.874.
Neonatal jaundice and its relationship to glucose-6-phosphate dehydrogenase (G6PD) status of healthy, term Chinese infants was evaluated in 220 G6PD-deficient infants, 26 intermediate infants who were observed for 3 weeks, and 116 normal (control) infants. Each infant was free of isoimmunisation, cephalhaematomas, or contusions. The mode of labour, method of delivery, and type of feeds had no appreciable effect on daily bilirubin levels. "Elevated" physiological jaundice was associated with normal and G6PD-deficient status; there was no increased haemolysis. G6PD-deficient status was associated with jaundice significantly raised especially in the first week of life, and prolonged beyond that of the "elevated" physiological jaundice. Significantly increased though mild haemolysis was observed. Close surveillance is therefore required for G6PD-deficient infants at least for the first week of life, the period of increased risk. With G6PD-intermediate infants, only the usual measures for normal infants are required.
对220名葡萄糖-6-磷酸脱氢酶（G6PD）缺乏的婴儿、26名观察3周的中间型婴儿以及116名正常（对照）婴儿，评估了新生儿黄疸及其与足月健康中国婴儿G6PD状态的关系。每名婴儿均无血型不合免疫、头颅血肿或挫伤。分娩方式、分娩方法及喂养类型对每日胆红素水平无明显影响。“生理性黄疸升高”与正常及G6PD缺乏状态相关；无溶血增加。G6PD缺乏状态与黄疸显著升高相关，尤其是在出生后第一周，且持续时间超过“生理性黄疸升高”，虽溶血轻微但显著增加。因此，至少在出生后第一周这一风险增加期，需要密切监测G6PD缺乏的婴儿。对于G6PD中间型婴儿，仅需采取正常婴儿的常规措施。
