Taira K, Mutoh H
Arch Histol Jpn. 1981 Sep;44(4):373-84. doi: 10.1679/aohc1950.44.373.
The Ito cell (fat-storing cell) in the liver of the lizard, snake and turtle was studied by electron microscopy. The Ito cell was positioned in the perisinusoidal space of Disse and contained characteristic fat droplets in all of the animals studied. The fat droplets in the Ito cells of turtles, fed commercially obtained pig liver, were numerous and large. The Ito cells contained fewer and smaller fat droplets in the lizards and snakes, caught in their natural habitat and sacrificed. There were frequently Ito cells without fat droplets, designated as empty Ito cells, in the snake liver. Dilated cisternae of rough endoplasmic reticulum were found in the Ito cells of the lizard and snake liver, but they were absent from the Ito cells of the turtle liver. It is suggested that the nutritional state of animals, especially the vitamin A concentration in the food, might induce these differences in the Ito cell.
利用电子显微镜对蜥蜴、蛇和龟肝脏中的伊托细胞（贮脂细胞）进行了研究。伊托细胞位于狄氏间隙的窦周隙内，在所研究的所有动物中均含有特征性的脂肪滴。喂食市售猪肝的龟的伊托细胞中的脂肪滴数量众多且体积较大。在自然栖息地捕获并处死后的蜥蜴和蛇的伊托细胞中，脂肪滴数量较少且体积较小。蛇肝脏中经常存在没有脂肪滴的伊托细胞，称为空伊托细胞。在蜥蜴和蛇肝脏的伊托细胞中发现了扩张的粗面内质网池，但龟肝脏的伊托细胞中没有。提示动物的营养状态，尤其是食物中的维生素A浓度，可能导致伊托细胞出现这些差异。
