人尿中的异锁链素。早期发育阶段及马方综合征患者体内的含量。
Desmosines in human urine. Amounts in early development and in Marfan's syndrome.
作者信息
Gunja-Smith Z, Boucek R J
出版信息
Biochem J. 1981 Mar 1;193(3):915-8. doi: 10.1042/bj1930915.
Abstract
Desmosines from 24 h human urine samples were isolated, characterized and quantified. The desmosines are in peptidyl form (1000--1500 molecular weight), and their amount is decreased by two-thirds between 7 and 25 years of age. Patients with Marfan's syndrome have significantly lower urinary amounts of desmosines than do comparable controls during the early development period.
摘要
从24小时的人类尿液样本中分离、鉴定并定量了异锁链素。异锁链素呈肽基形式（分子量为1000 - 1500），其含量在7至25岁之间减少了三分之二。在早期发育阶段，马凡氏综合征患者尿液中的异锁链素含量显著低于相应的对照组。
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