新生儿轮状病毒感染
Rotavirus infections of neonates.
作者信息
Murphy A M, Albrey M B, Crewe E B
出版信息
Lancet. 1977 Dec 3;2(8049):1149-50. doi: 10.1016/s0140-6736(77)91538-0.
Faecal specimens from 628 newborn babies in the nurseries of six metropolitan hospitals were examined by electron microscopy for rotaviruses. 304 babies (49%) were found to be excreting virus. All those infected were in five nurseries; viruses were not detected in specimens from the sixth nursery. Two nurseries were studied for 9 mo and another for 11 mo and rotaviruses were found consistently in 40-50% of stools examined. There was no seasonal variation. None of the neonates under the age of one day were infected but by the age of three to four days approximately 50% were excreting virus. Most of those shedding virus were symptom-free but 84 (28%) had diarrhoea. Persisting endemic rotavirus infection is apparently common in hospital nurseries in Sydney. The virus is probably transmitted by environmental spread from neonate to neonate.
对来自六家大城市医院托儿所的628名新生儿的粪便样本进行了电子显微镜检查，以检测轮状病毒。发现304名婴儿（49%）正在排出病毒。所有受感染的婴儿都在五个托儿所；在第六个托儿所的样本中未检测到病毒。对两个托儿所进行了9个月的研究，另一个进行了11个月的研究，在所检查的粪便中，40%-50%的样本中始终能发现轮状病毒。没有季节性变化。一天以下的新生儿均未感染，但到三至四天大时，约50%的婴儿正在排出病毒。大多数排出病毒的婴儿没有症状，但有84名（28%）出现腹泻。持续性地方性轮状病毒感染在悉尼的医院托儿所显然很常见。该病毒可能通过环境传播在新生儿之间传播。
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