新生儿无症状地方性轮状病毒感染
Asymptomatic endemic rotavirus infections in the newborn.
作者信息
Chrystie I L, Totterdell B M, Banatvala J E
出版信息
Lancet. 1978 Jun 3;1(8075):1176-8. doi: 10.1016/s0140-6736(78)90967-4.
Between May 1, 1976, and May 14, 1977, 343 (32.5%) of 1056 5-day-old babies in newborn nurseries excreted rotaviruses. The infection-rate was highest during winter (49%). 76% of infected babies at this time were bottle-fed. 41% of neonates excreted low amounts of virus (less than or equal to 10(8) particles/g faeces); older children tended to excrete greater than 10(10) particles/g faeces. Infected breast-fed babies excreted less virus than those who were bottle-fed. Stools of breast-fed babies often contained clumps of complete "smooth" rotavirus particles. When the newborn nurseries were transferred to a newly built hospital wing, infection appeared in the new wards, including those admitting only new patients, within a short period. Infection was either mild (8%) or symptomless (92%), and even babies with symptoms required no treatment.
在1976年5月1日至1977年5月14日期间，新生儿病房中1056名5日龄婴儿中有343名（32.5%）排出轮状病毒。感染率在冬季最高（49%）。此时76%的受感染婴儿采用奶瓶喂养。41%的新生儿排出少量病毒（小于或等于10⁸颗粒/克粪便）；年龄较大的儿童往往排出大于10¹⁰颗粒/克粪便。受感染的母乳喂养婴儿排出的病毒比奶瓶喂养的婴儿少。母乳喂养婴儿的粪便中常含有成团的完整“光滑”轮状病毒颗粒。当新生儿病房迁至新建的医院侧翼时，新病房（包括仅收治新患者的病房）在短时间内出现了感染情况。感染要么轻微（8%），要么无症状（92%），即使有症状的婴儿也无需治疗。
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