• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

慢性猫主动睡眠期间腰段运动神经元兴奋性的突触后控制

Postsynaptic control of lumbar motoneuron excitability during active sleep in the chronic cat.

作者信息

Morales F, Chase M H

出版信息

Brain Res. 1981 Nov 30;225(2):279-95. doi: 10.1016/0006-8993(81)90836-2.

DOI:10.1016/0006-8993(81)90836-2
PMID:7306790
Abstract

A correlated intracellular and extracellular study of lumbar motoneuron excitability during sleep and wakefulness was performed in the chronic, unanesthetized, undrugged, normally respiring cat. Experiments were designed to reveal the extent to which hypotonia during active sleep in mammals is dependent on postsynaptic inhibition of somatic motoneurons. Variations in the antidromic field potential, antidromic and orthodromic spike, EPSP, membrane input resistance and rheobasic current were studied. No change in motoneuron excitability occurred when quiet wakefulness was compared to quiet sleep. A decrease in excitability was present, due to postsynaptic inhibition, during active sleep. Further phasic decreases in excitability, also due to postsynaptic inhibition, occurred during active sleep in conjunction with clusters of rapid eye movements.

摘要

在慢性、未麻醉、未用药、正常呼吸的猫身上,进行了一项关于睡眠和清醒期间腰段运动神经元兴奋性的细胞内和细胞外相关研究。实验旨在揭示哺乳动物主动睡眠期间的肌张力减退在多大程度上依赖于躯体运动神经元的突触后抑制。研究了逆向场电位、逆向和正向动作电位、兴奋性突触后电位、膜输入电阻和基强度电流的变化。将安静清醒与安静睡眠相比较时,运动神经元兴奋性没有变化。在主动睡眠期间,由于突触后抑制,兴奋性降低。在主动睡眠期间,伴随着快速眼动簇,还会出现由于突触后抑制导致的兴奋性进一步阶段性降低。

相似文献

1
Postsynaptic control of lumbar motoneuron excitability during active sleep in the chronic cat.慢性猫主动睡眠期间腰段运动神经元兴奋性的突触后控制
Brain Res. 1981 Nov 30;225(2):279-95. doi: 10.1016/0006-8993(81)90836-2.
2
Synaptic mechanisms and circuitry involved in motoneuron control during sleep.睡眠期间运动神经元控制所涉及的突触机制和神经回路。
Int Rev Neurobiol. 1983;24:213-58. doi: 10.1016/s0074-7742(08)60223-8.
3
Phasic changes in motoneuron membrane potential during REM periods of active sleep.快速眼动睡眠期主动睡眠期间运动神经元膜电位的阶段性变化。
Neurosci Lett. 1982 Dec 30;34(2):177-82. doi: 10.1016/0304-3940(82)90172-0.
4
The postsynaptic inhibitory control of lumbar motoneurons during the atonia of active sleep: effect of strychnine on motoneuron properties.主动睡眠无张力状态下腰段运动神经元的突触后抑制性控制:士的宁对运动神经元特性的影响。
J Neurosci. 1991 Sep;11(9):2804-11. doi: 10.1523/JNEUROSCI.11-09-02804.1991.
5
Effect of stimulation of the nucleus reticularis gigantocellularis on the membrane potential of cat lumbar motoneurons during sleep and wakefulness.睡眠和觉醒期间刺激巨细胞网状核对猫腰段运动神经元膜电位的影响。
Brain Res. 1986 Oct 29;386(1-2):237-44. doi: 10.1016/0006-8993(86)90160-5.
6
Hyperpolarizing membrane responses induced in lumbar motoneurons by stimulation of the nucleus reticularis pontis oralis during active sleep.在主动睡眠期间,刺激脑桥嘴侧网状核在腰段运动神经元中诱发的超极化膜反应。
Brain Res. 1982 Sep 30;248(2):267-73. doi: 10.1016/0006-8993(82)90584-4.
7
Behavioral state-specific inhibitory postsynaptic potentials impinge on cat lumbar motoneurons during active sleep.
Exp Neurol. 1987 Nov;98(2):418-35. doi: 10.1016/0014-4886(87)90252-4.
8
Membrane potential and input resistance of cat spinal motoneurons in wakefulness and sleep.清醒和睡眠状态下猫脊髓运动神经元的膜电位和输入电阻
Behav Brain Res. 1981 Mar;2(2):231-6. doi: 10.1016/0166-4328(81)90060-7.
9
The motor inhibitory system operating during active sleep is tonically suppressed by GABAergic mechanisms during other states.在活跃睡眠期间起作用的运动抑制系统在其他状态下会被GABA能机制持续性抑制。
J Neurophysiol. 2001 Oct;86(4):1908-15. doi: 10.1152/jn.2001.86.4.1908.
10
Activity of rostral trigeminal sensory neurons in the cat during wakefulness and sleep.猫在清醒和睡眠期间延髓三叉神经感觉神经元的活动。
J Neurophysiol. 1995 Jun;73(6):2486-98. doi: 10.1152/jn.1995.73.6.2486.

引用本文的文献

1
Meta-analysis of biological variables' impact on spinal motoneuron electrophysiology data.生物变量对脊髓运动神经元电生理数据影响的荟萃分析。
J Neurophysiol. 2020 Apr 1;123(4):1380-1391. doi: 10.1152/jn.00378.2019. Epub 2020 Feb 19.
2
Do Quiescence and Wasp Venom-Induced Lethargy Share Common Neuronal Mechanisms in Cockroaches?
PLoS One. 2017 Jan 3;12(1):e0168032. doi: 10.1371/journal.pone.0168032. eCollection 2017.
3
Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms.上呼吸道的神经控制:呼吸及状态依赖机制
Compr Physiol. 2016 Sep 15;6(4):1801-1850. doi: 10.1002/cphy.c160002.
4
Postsynaptic inhibition of hypoglossal motoneurons produces atonia of the genioglossal muscle during rapid eye movement sleep.舌下运动神经元的突触后抑制在快速眼动睡眠期间会导致颏舌肌弛缓。
Sleep. 2015 Jan 1;38(1):139-46. doi: 10.5665/sleep.4340.
5
State-dependent control of lumbar motoneurons by the hypocretinergic system.下丘脑食欲素能系统对腰运动神经元的状态依赖性控制。
Exp Neurol. 2010 Feb;221(2):335-45. doi: 10.1016/j.expneurol.2009.11.020. Epub 2009 Dec 3.
6
Confirmation of the consensus that glycinergic postsynaptic inhibition is responsible for the atonia of REM sleep.甘氨酸能突触后抑制导致快速眼动睡眠肌张力缺失这一共识得到证实。
Sleep. 2008 Nov;31(11):1487-91. doi: 10.1093/sleep/31.11.1487.
7
Glycine-mediated postsynaptic inhibition is responsible for REM sleep atonia.甘氨酸介导的突触后抑制是快速眼动睡眠期肌张力缺失的原因。
Sleep. 2008 Nov;31(11):1483-6. doi: 10.1093/sleep/31.11.1483.
8
Are all motoneurons created equal in the eyes of REM sleep and the mechanisms of muscle atonia?在快速眼动睡眠及肌肉张力缺失机制的视角下,所有运动神经元都是等同的吗?
Sleep. 2008 Nov;31(11):1479-82. doi: 10.1093/sleep/31.11.1479.
9
c-fos expression in brainstem premotor interneurons during cholinergically induced active sleep in the cat.猫在胆碱能诱导的主动睡眠期间脑干运动前中间神经元中的c-fos表达
J Neurosci. 1999 Nov 1;19(21):9508-18. doi: 10.1523/JNEUROSCI.19-21-09508.1999.
10
Rostral brainstem contributes to medullary inhibition of muscle tone.延髓上部脑干对肌张力的延髓抑制起作用。
Brain Res. 1983 Jun 6;268(2):344-8. doi: 10.1016/0006-8993(83)90501-2.