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乙醇对N-亚硝基二甲胺致癌作用的影响。

Influence of ethyl alcohol on carcinogenesis with N-nitrosodimethylamine.

作者信息

Griciute L, Castegnaro M, Bereziat J C

出版信息

Cancer Lett. 1981 Sep;13(4):345-52. doi: 10.1016/0304-3835(81)90063-x.

DOI:10.1016/0304-3835(81)90063-x
PMID:7306961
Abstract

This paper presents the results of an experiment on the combined action of nitrosodimethylamine and ethyl alcohol in C57BL mice. As shown, alcohol can act to change the target organ of that liver carcinogen by favouring development of olfactory neuroepitheliomas, which infiltrate the frontal lobe of the brain.

摘要

本文介绍了一项关于亚硝基二甲胺和乙醇对C57BL小鼠联合作用的实验结果。结果表明,酒精可通过促进嗅神经上皮瘤的发展来改变该肝脏致癌物的靶器官,嗅神经上皮瘤会浸润大脑额叶。

相似文献

1
Influence of ethyl alcohol on carcinogenesis with N-nitrosodimethylamine.乙醇对N-亚硝基二甲胺致癌作用的影响。
Cancer Lett. 1981 Sep;13(4):345-52. doi: 10.1016/0304-3835(81)90063-x.
2
Chemically induced esthesioneuroblastomas in rats.大鼠化学诱导的嗅神经母细胞瘤
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 Jun 15;86(2):113-9. doi: 10.1007/BF00283998.
3
[Carcinogenic properties of nitrosodimethylamine when combined with benzene, cadmium, boron or ethanol].[亚硝基二甲胺与苯、镉、硼或乙醇联合时的致癌特性]
Vopr Onkol. 1986;32(1):80-4.
4
Tumors of the respiratory tract induced by inhalation of bis(chloromethyl)ether.吸入双(氯甲基)醚所致呼吸道肿瘤
Arch Environ Health. 1971 Aug;23(2):135-6. doi: 10.1080/00039896.1971.10665970.
5
Synergistic effect of ferric oxide on dimethylnitrosamine carcinogenesis in the Syrian golden hamster.三氧化二铁对叙利亚金仓鼠二甲基亚硝胺致癌作用的协同效应。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1973;79(1):31-8. doi: 10.1007/BF00284337.
6
[Morphology and morphogenesis of nasal cavity tumors in hamsters induced by diethylnitrosamine (author's transl)].
Beitr Pathol. 1974 Feb;151(2):134-56.
7
Carcinogenic action of quinoxaline 1,4-dioxide in rats.
J Natl Cancer Inst. 1975 Jul;55(1):137-46. doi: 10.1093/jnci/55.1.137.
8
Histogenesis of malignant liver tumors induced by dimethylnitrosamine. An experimental study in Syrian hamsters.
J Natl Cancer Inst. 1967 Dec;39(6):1099-111.
9
Carcinogenesis in rats by nitrosodimethylamine and other nitrosomethylalkylamines at low doses.
Cancer Lett. 1984 Feb;22(1):83-8. doi: 10.1016/0304-3835(84)90047-8.
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Investigation into the pharmacodynamics of the carcinogen N-nitrodimethylamine.
IARC Sci Publ. 1987(84):150-2.

引用本文的文献

1
Risk assessment of nitrosamines in food.食品中亚硝胺的风险评估。
EFSA J. 2023 Mar 28;21(3):e07884. doi: 10.2903/j.efsa.2023.7884. eCollection 2023 Mar.
2
Effect of chronic alcohol consumption on tumor incidence due to dimethylnitrosamine administration.长期饮酒对给予二甲基亚硝胺所致肿瘤发生率的影响。
J Cancer Res Clin Oncol. 1983;106(1):58-64. doi: 10.1007/BF00399898.
3
Covalent binding of aflatoxin B1 to liver DNA in rats pretreated with ethanol.黄曲霉毒素B1与经乙醇预处理的大鼠肝脏DNA的共价结合。
Experientia. 1985 Oct 15;41(10):1338-40. doi: 10.1007/BF01952084.
4
Influence of ethanol induction on the metabolic activation of genotoxic agents by isolated rat hepatocytes.
Arch Toxicol. 1985 Sep;57(4):217-21. doi: 10.1007/BF00324780.
5
Chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1982.《致癌潜能数据库的时间顺序补充:截至1982年12月发表的动物生物测定标准化结果》
Environ Health Perspect. 1986 Aug;67:161-200. doi: 10.1289/ehp.8667161.
6
Enhancing effect of ethanol on aflatoxin B1-induced hepatocarcinogenesis in male ACI/N rats.乙醇对雄性 ACI/N 大鼠黄曲霉毒素 B1 诱导的肝癌发生的增强作用。
Jpn J Cancer Res. 1989 Jun;80(6):526-30. doi: 10.1111/j.1349-7006.1989.tb01671.x.
7
Hepatocellular carcinoma, alcohol, and cirrhosis: facts and hypotheses.肝细胞癌、酒精与肝硬化:事实与假说
Dig Dis Sci. 1991 Aug;36(8):1137-42. doi: 10.1007/BF01297461.