多潘立酮的内分泌效应：一种外周多巴胺阻断剂。
Endocrine effects of domperidone: a peripheral dopamine blocking agent.
作者信息
Brown G M, Verhaegan H, Van Wimersma Greidanus T B, Brugmans J
出版信息
Clin Endocrinol (Oxf). 1981 Sep;15(3):275-82. doi: 10.1111/j.1365-2265.1981.tb00666.x.
Abstract
In the present study, effects of domperidone, a peripheral dopamine blocking agent, on prolactin and growth hormone were examined to determine whether dopamine regulation of these hormones involved structures external to the blood-brain barrier. A clearcut elevation in prolactin was produced by domperidone. GH response to apomorphine was partially blocked by domperidone.
摘要
在本研究中，检测了外周多巴胺阻断剂多潘立酮对催乳素和生长激素的影响，以确定多巴胺对这些激素的调节是否涉及血脑屏障以外的结构。多潘立酮使催乳素明显升高。多潘立酮部分阻断了生长激素对阿扑吗啡的反应。
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