Fortýnová J, Bakos K, Pradácová J
Czech Med. 1981;4(3):137-46.
Bone marrow scintigraphy was performed in 29 patients with hemopoietic depletion states of various etiology. Two tracers were used for visualization of the marrow: 99mTc-sulphur-colloid and 111InCl3, some patients being examined by both indicators. 111InCl3 is bound on transferrin and is adsorbed on the surface of reticulocytes and erythroblasts). The scintillation camera PHO GAMMA SEARLE IV fitted with moving table and computer CLINCOM was used, so that whole body images were obtained. The comparison of all scans and marrow puncture smears was done. In patients with aplastic anemia with both hyperplastic or hypoplastic marrow good correlation of bone marrow scans and sternal puncture smears was found. In several cases the scintigraphic examination helped to establish a diagnosis of marrow depletion state. A peculiar disadvantage of the imaging method with either 99mTc-sulphur-colloid or 111InCl3 is that it shows the disorders in erythropoietic and reticuloendothelial cells, whereas the defects in myelopoietic cell series and platelet precursors are not provable. According to literature data, great attention is paid to the prognostic value of scintigraphic examination in aplastic anemia.
对29例不同病因造血功能衰竭状态的患者进行了骨髓闪烁显像。使用了两种示踪剂来显示骨髓：99mTc-硫胶体和111InCl3，部分患者同时接受了这两种指标的检查。111InCl3与转铁蛋白结合并吸附在网织红细胞和成红细胞表面。使用配备移动检查床的PHO GAMMA SEARLE IV闪烁相机和CLINCOM计算机，从而获得全身图像。对所有扫描结果与骨髓穿刺涂片进行了比较。在再生障碍性贫血患者中，无论骨髓增生或增生低下，骨髓扫描与胸骨穿刺涂片均有良好的相关性。在一些病例中，闪烁显像检查有助于确诊骨髓衰竭状态。使用99mTc-硫胶体或111InCl3的成像方法的一个特殊缺点是，它显示的是红细胞生成和网状内皮细胞的紊乱，而髓系细胞系列和血小板前体的缺陷无法显示。根据文献资料，闪烁显像检查在再生障碍性贫血中的预后价值受到高度关注。
