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自然计划生育排卵法的前瞻性多中心试验。II. 有效性阶段。

A prospective multicentre trial of the ovulation method of natural family planning. II. The effectiveness phase.

出版信息

Fertil Steril. 1981 Nov;36(5):591-8. doi: 10.1016/s0015-0282(16)45856-5.

Abstract

A five-country prospective study was undertaken to determine the effectiveness of the ovulation method of natural family planning. After successful completion of a teaching phase of three cycles, 725 subjects entered a 13-cycle effectiveness phase and contributed 7514 cycles of observation. The overall cumulative net probability of discontinuation for the effectiveness study after 13 cycles was 35.6%, 19.6% due to pregnancy. Pregnancy rates per 100 woman-years calculated using the modified Pearl index were as follows: conscious departure from the rules of the method, 15.4; inaccurate application of instructions, 3.5; method failure, 2.8; inadequate teaching, 0.4; and uncertain, 0.5.

摘要

开展了一项五国前瞻性研究,以确定自然计划生育排卵法的有效性。在成功完成三个周期的教学阶段后,725名受试者进入了为期13个周期的有效性阶段,并提供了7514个观察周期。有效性研究在13个周期后的总体累积净停用概率为35.6%,其中19.6%是由于怀孕。使用改良的佩尔指数计算的每100妇女年妊娠率如下:故意违反方法规则,15.4;说明应用不准确,3.5;方法失败,2.8;教学不足,0.4;以及不确定,0.5。

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