Harkins S W
Int J Neurosci. 1981;15(3):165-70. doi: 10.3109/00207458108985910.
Central transmission time (CTT) between the first and fifth wave of the brainstem auditory evoked potential (BAEP) was assessed in a group of patients clinically diagnosed as suffering from presenile dementia of the Alzheimer's type. CTT was significantly longer in patients compared to healthy young and elderly volunteers. Age per se did not result in prolonged peak latencies or CTT. These results indicate that far-field and early near-field evoked potentials may be of utility in early diagnosis of central nervous system dysfunction associated with diffuse degenerative diseases such as Alzheimer's and related diseases.
在一组临床诊断为阿尔茨海默型早老性痴呆的患者中，评估了脑干听觉诱发电位（BAEP）第一波与第五波之间的中枢传导时间（CTT）。与健康的年轻和老年志愿者相比，患者的CTT明显更长。年龄本身并不会导致峰值潜伏期延长或CTT延长。这些结果表明，远场和早期近场诱发电位可能有助于早期诊断与阿尔茨海默病及相关疾病等弥漫性退行性疾病相关的中枢神经系统功能障碍。
