用于评估胎儿肺成熟度的羊水荧光偏振值。

Amniotic fluid fluorescence polarisation values for assessing fetal lung maturation.

作者信息

Legge M, Potter H C

出版信息

J Clin Pathol. 1981 Oct;34(10):1094-6. doi: 10.1136/jcp.34.10.1094.

DOI:10.1136/jcp.34.10.1094

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC494371/

Abstract

The fluorescence probe 1,6, diphenyl-1,3,5-hexatriene was used to determine the micro-viscosity of third trimester amniotic fluid samples utilising an Aminco Bowman spectrofluorometer fitted with a polariser prism. The results were related to the lecithin sphingomyelin (L:S) ratio. A fluorescence polarisation value of 0.360 corresponded to an L:S ratio of 2.0 in uncomplicated and diabetic pregnancies. Pregnancies complicated by Rhesus disease gave significantly different fluorescence polarisation values when compared with the uncomplicated pregnancies.

摘要

荧光探针1,6 - 二苯基 - 1,3,5 - 己三烯用于通过配备偏光棱镜的Aminco Bowman荧光分光光度计测定孕晚期羊水样本的微粘度。结果与卵磷脂鞘磷脂（L:S）比值相关。在未合并症和糖尿病妊娠中，荧光偏振值0.360对应L:S比值为2.0。与未合并症妊娠相比，合并恒河猴血型不合疾病的妊娠荧光偏振值有显著差异。

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本文引用的文献

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Amniotic fluid fluorescence polarization value as a predictor of respiratory distress syndrome.羊水荧光偏振值作为呼吸窘迫综合征的预测指标

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Microviscosity and order in the hydrocarbon region of micelles and membranes determined with fluorescent probes. I. Synthetic micelles.用荧光探针测定胶束和膜的烃区域中的微粘度和有序性。I. 合成胶束。

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A new method for assessment of fetal lung maturity.一种评估胎儿肺成熟度的新方法。

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Microviscosity of amniotic fluid phospholipids, and its importance in determining fetal lung maturity.

Clin Chem. 1979 Jan;25(1):64-7.

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Pediatrics. 1979 Feb;63(2):213-8.

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