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用于评估胎儿肺成熟度的羊水荧光偏振值。

Amniotic fluid fluorescence polarisation values for assessing fetal lung maturation.

作者信息

Legge M, Potter H C

出版信息

J Clin Pathol. 1981 Oct;34(10):1094-6. doi: 10.1136/jcp.34.10.1094.

DOI:10.1136/jcp.34.10.1094
PMID:7309891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC494371/
Abstract

The fluorescence probe 1,6, diphenyl-1,3,5-hexatriene was used to determine the micro-viscosity of third trimester amniotic fluid samples utilising an Aminco Bowman spectrofluorometer fitted with a polariser prism. The results were related to the lecithin sphingomyelin (L:S) ratio. A fluorescence polarisation value of 0.360 corresponded to an L:S ratio of 2.0 in uncomplicated and diabetic pregnancies. Pregnancies complicated by Rhesus disease gave significantly different fluorescence polarisation values when compared with the uncomplicated pregnancies.

摘要

荧光探针1,6 - 二苯基 - 1,3,5 - 己三烯用于通过配备偏光棱镜的Aminco Bowman荧光分光光度计测定孕晚期羊水样本的微粘度。结果与卵磷脂鞘磷脂（L:S）比值相关。在未合并症和糖尿病妊娠中，荧光偏振值0.360对应L:S比值为2.0。与未合并症妊娠相比，合并恒河猴血型不合疾病的妊娠荧光偏振值有显著差异。

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Amniotic fluid fluorescence polarisation values for assessing fetal lung maturation.用于评估胎儿肺成熟度的羊水荧光偏振值。
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本文引用的文献

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Amniotic fluid fluorescence polarization value as a predictor of respiratory distress syndrome.羊水荧光偏振值作为呼吸窘迫综合征的预测指标
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Isolation, characterization, and surface chemistry of a surface-active fraction from dog lung.
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Dynamics of the hydrocarbon layer in liposomes of lecithin and sphingomyelin containing dicetylphosphate.含磷酸二鲸蜡酯的卵磷脂和鞘磷脂脂质体中烃层的动力学
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Microviscosity and order in the hydrocarbon region of phospholipid and phospholipid-cholesterol dispersions determined with fluorescent probes.用荧光探针测定磷脂及磷脂 - 胆固醇分散体系烃类区域的微粘度和有序性。
Biochemistry. 1973 Jan 30;12(3):521-8. doi: 10.1021/bi00727a026.
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Microviscosity and order in the hydrocarbon region of micelles and membranes determined with fluorescent probes. I. Synthetic micelles.用荧光探针测定胶束和膜的烃区域中的微粘度和有序性。I. 合成胶束。
Biochemistry. 1971 May 25;10(11):2106-13. doi: 10.1021/bi00787a023.
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A new method for assessment of fetal lung maturity.一种评估胎儿肺成熟度的新方法。
Br J Obstet Gynaecol. 1976 Nov;83(11):838-44. doi: 10.1111/j.1471-0528.1976.tb00757.x.
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Microviscosity of amniotic fluid phospholipids, and its importance in determining fetal lung maturity.
Clin Chem. 1979 Jan;25(1):64-7.
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Amniotic fluid microviscosity determined by fluorescence polarization: methodology and relation to gestational age.通过荧光偏振测定羊水微粘度：方法及与孕周的关系
Pediatrics. 1979 Feb;63(2):213-8.

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