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视觉诱发电位和抑制功能的寿命期变化

Life-span alterations in visually evoked potentials and inhibitory function.

作者信息

Dustman R E, Snyder E W, Schlehuber C J

出版信息

Neurobiol Aging. 1981 Fall;2(3):187-92. doi: 10.1016/0197-4580(81)90019-1.

DOI:10.1016/0197-4580(81)90019-1
PMID:7312096
Abstract

Visually evoked potentials (VEPs) elicited by patterned and unpatterned flashes were recorded from 211 healthy males aged 4-90 years. A measure of similarity between the two kinds of VEPs was obtained by correlating the digital values comprising the two waveforms. Across the life-span, correlations followed a U-shaped curve; patterned and unpatterned flash VEPs were most alike for the youngest and oldest subjects. This age effect, localized to scalp areas overlying visual cortex, is compatible with a concept of reduced inhibitory functioning within the visual systems of the young and the old. At central scalp, patterned and unpatterned flash VEP waveforms were more effectively differentiated by the right hemisphere. This observation agrees that the right hemisphere specializes in analyses of spatial material.

摘要

从211名年龄在4至90岁的健康男性身上记录了由图案化和非图案化闪光诱发的视觉诱发电位(VEP)。通过对构成两种波形的数字值进行相关性分析,获得了两种VEP之间的相似性度量。在整个生命周期中,相关性呈U形曲线;对于最年轻和最年长的受试者,图案化和非图案化闪光VEP最为相似。这种年龄效应局限于视觉皮层上方的头皮区域,与年轻人和老年人视觉系统中抑制功能降低的概念相符。在头皮中央,右半球能更有效地区分图案化和非图案化闪光VEP波形。这一观察结果与右半球专门分析空间材料的观点一致。

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