Winikoff B, Debrovner C H
Obstet Gynecol. 1981 Dec;58(6):678-84.
The correlation of maternal and paternal physical characteristics to the weight of the newborn infant was investigated. It was found that a different anthropomorphic variable best explained the outcome in each group when mothers were divided by weight for height. In women of low weight for height, weight gain was most significantly associated with birth weight (P less than .01); and in women of intermediate weight for height, the significant variable was maternal prepregnancy weight (P less than .01); in women of high weight for height the outcome was best explained by maternal height (P less than .05). The model accounted for 17, 21, and 32% of the variance in birth weight in the 3 weight-for-height groups, respectively. It appears that the relative value of genetic and environmental factors may be different depending on the body type of the mother. It is postulated that other genetic and environmental factors, including smoking, alcohol ingestion, and exact gestation age, may be of significance. The conclusions of this study differ from those of previously reported studies. Possible explanations include variable population homogeneity and different socioeconomic groups studied as well as the obscuring of biologically significant variables if outcomes in subjects with different body types are not analyzed separately.
研究了母亲和父亲的身体特征与新生儿体重之间的相关性。研究发现,当根据身高体重将母亲分组时,不同的人体测量变量能最好地解释每组的结果。在身高体重较低的女性中,体重增加与出生体重最显著相关(P小于0.01);在身高体重中等的女性中,显著变量是母亲孕前体重(P小于0.01);在身高体重较高的女性中,母亲身高能最好地解释结果(P小于0.05)。该模型分别解释了三个身高体重组中出生体重方差的17%、21%和32%。似乎遗传和环境因素的相对价值可能因母亲的体型而异。据推测,其他遗传和环境因素,包括吸烟、饮酒和确切的妊娠年龄,可能具有重要意义。本研究的结论与先前报道的研究不同。可能的解释包括所研究人群的同质性不同、社会经济群体不同,以及如果不分别分析不同体型受试者的结果,生物学上有意义的变量可能会被掩盖。