Dillon W P, Egan E A
Obstet Gynecol. 1981 Dec;58(6):685-90.
A 3-year experience during which fetal welfare was a major factor in the management of patients delivering between 24 and 27 weeks' gestation is presented. Sixty-two cases of women for whom prenatal assigned gestational age was between 24 and 27 weeks and who had a live fetus on admission were reviewed. Using discharge from the hospital as definition for survival, 34 of the 62 infants (55%) survived. Survival rates ranged from 36% at 24 weeks' gestation to 76% at 27 weeks' gestation. Three of the 34 survivors had major continuing problems at discharge. Of the various strategies used to improve perinatal outcome, the antenatal administration of betamethasone was associated with a significant (P less than .03) improvement in infant survival. The authors are encouraged by these results, which indicate that aggressive antenatal and postnatal efforts for pregnancies with gestational ages between 24 and 27 weeks are cost-effective, productive, and worthwhile.
本文介绍了一项为期3年的经验，在此期间，胎儿健康状况是妊娠24至27周分娩患者管理中的一个主要因素。回顾了62例产前确定孕周在24至27周且入院时胎儿存活的女性病例。以出院作为存活的定义，62例婴儿中有34例（55%）存活。存活率从妊娠24周时的36%到妊娠27周时的76%不等。34名存活者中有3名在出院时有严重的持续问题。在用于改善围产期结局的各种策略中，产前给予倍他米松与婴儿存活率的显著提高（P<0.03）相关。这些结果让作者备受鼓舞，表明对孕周在24至27周的妊娠进行积极的产前和产后努力是具有成本效益、富有成效且值得的。
