Yen J K, Bourke R S, Nelson L R, Popp A J
J Neurol Neurosurg Psychiatry. 1978 Dec;41(12):1125-30. doi: 10.1136/jnnp.41.12.1125.
A scheme to quantitate the clinical neurological status of the seriously head-injured patient has been devised. The neurological parameters used to quantify the degree of injury are based on neurological functions which have previously been accepted as indicators of the severity of the head injury. A numerical value is assigned to each parameter with emphasis on defining the level of consciousness. The accrued point total of each examination represents the neurological status of the patient at that time. Mean values and standard error from the means are determined from repeated examinations during a single 24 hour period, and are plotted against days after injury. From this graph a line which represents the rate of clinical recovery is determined by least squares analysis. General intensive care nurses were trained to score patients independently; their determinations were found to be in statistical agreement with scores derived from examinations by the attending physicians. The data presented highlight the effects of hypoxaemia in impeding the rate of neurological recovery from a serious head injury. This simple clinical analytical scheme for the quantitative assessment of patients with head injury permits evaluation of the efficacy of various modes of therapy in altering the rate of recovery.
已设计出一种对严重颅脑损伤患者的临床神经学状况进行量化的方案。用于量化损伤程度的神经学参数基于先前已被视为颅脑损伤严重程度指标的神经学功能。每个参数都被赋予一个数值,重点是定义意识水平。每次检查的累计总分代表患者当时的神经学状况。在单个24小时期间内通过重复检查确定均值和均值标准误差,并将其与受伤后的天数进行绘图。通过该图表,通过最小二乘法分析确定代表临床恢复率的线。对普通重症监护护士进行培训,使其能够独立对患者进行评分;发现他们的评定结果与主治医生检查得出的评分在统计学上一致。所呈现的数据突出了低氧血症对严重颅脑损伤神经学恢复速率的阻碍作用。这种用于定量评估颅脑损伤患者的简单临床分析方案允许评估各种治疗模式在改变恢复速率方面的疗效。