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QUANTITATIVE CLINICAL NEUROLOGICAL TESTING. I. A STUDY OF A BATTERY OF TESTS DESIGNED TO EVALUATE IN PART THE NEUROLOGICAL FUNCTION OF PATIENTS WITH MULTIPLE SCLEROSIS AND ITS USE IN A THERAPEUTIC TRIAL.定量临床神经学检测。一、一组旨在部分评估多发性硬化症患者神经功能的检测方法的研究及其在一项治疗试验中的应用。
Ann N Y Acad Sci. 1965 Mar 31;122:480-505. doi: 10.1111/j.1749-6632.1965.tb20231.x.
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A new scale for evaluating disability in multiple sclerosis.一种评估多发性硬化症残疾程度的新量表。
Neurology. 1955 Aug;5(8):580-3. doi: 10.1212/wnl.5.8.580.
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Assessment and prognosis in hemiplegia.偏瘫的评估与预后
Lancet. 1953 Aug 8;265(6780):266-9. doi: 10.1016/s0140-6736(53)91128-3.
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Factors affecting the clinical corse of patients with severe head injuries. 1. Influence of biological factors. 2. Significance of posttraumatic coma.影响重型颅脑损伤患者临床病程的因素。1. 生物学因素的影响。2. 创伤后昏迷的意义。
J Neurosurg. 1968 Sep;29(3):242-51. doi: 10.3171/jns.1968.29.3.0242.
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Neurosurgical watch sheet for craniocerebral trauma.颅脑创伤神经外科观察表
J Trauma. 1968 Jan;8(1):29-31. doi: 10.1097/00005373-196801000-00004.
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Assessment of coma and impaired consciousness. A practical scale.昏迷与意识障碍评估。实用量表。
Lancet. 1974 Jul 13;2(7872):81-4. doi: 10.1016/s0140-6736(74)91639-0.
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Prognosis after head injury based on early clinical examination.基于早期临床检查的头部损伤预后
Lancet. 1973 Sep 22;2(7830):631-5. doi: 10.1016/s0140-6736(73)92477-x.
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Persistent vegetative state after brain damage. A syndrome in search of a name.脑损伤后的持续性植物状态。一种有待命名的综合征。
Lancet. 1972 Apr 1;1(7753):734-7. doi: 10.1016/s0140-6736(72)90242-5.
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Aspects of coma after severe head injury.重度颅脑损伤后的昏迷情况
Lancet. 1977 Apr 23;1(8017):878-81. doi: 10.1016/s0140-6736(77)91201-6.
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Predicting outcome in individual patients after severe head injury.预测重度颅脑损伤后个体患者的预后。
Lancet. 1976 May 15;1(7968):1031-4. doi: 10.1016/s0140-6736(76)92215-7.

重型颅脑损伤后临床神经功能状态的数字分级

Numerical grading of clinical neurological status after serious head injury.

作者信息

Yen J K, Bourke R S, Nelson L R, Popp A J

出版信息

J Neurol Neurosurg Psychiatry. 1978 Dec;41(12):1125-30. doi: 10.1136/jnnp.41.12.1125.

DOI:10.1136/jnnp.41.12.1125
PMID:731256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC493242/
Abstract

A scheme to quantitate the clinical neurological status of the seriously head-injured patient has been devised. The neurological parameters used to quantify the degree of injury are based on neurological functions which have previously been accepted as indicators of the severity of the head injury. A numerical value is assigned to each parameter with emphasis on defining the level of consciousness. The accrued point total of each examination represents the neurological status of the patient at that time. Mean values and standard error from the means are determined from repeated examinations during a single 24 hour period, and are plotted against days after injury. From this graph a line which represents the rate of clinical recovery is determined by least squares analysis. General intensive care nurses were trained to score patients independently; their determinations were found to be in statistical agreement with scores derived from examinations by the attending physicians. The data presented highlight the effects of hypoxaemia in impeding the rate of neurological recovery from a serious head injury. This simple clinical analytical scheme for the quantitative assessment of patients with head injury permits evaluation of the efficacy of various modes of therapy in altering the rate of recovery.

摘要

已设计出一种对严重颅脑损伤患者的临床神经学状况进行量化的方案。用于量化损伤程度的神经学参数基于先前已被视为颅脑损伤严重程度指标的神经学功能。每个参数都被赋予一个数值,重点是定义意识水平。每次检查的累计总分代表患者当时的神经学状况。在单个24小时期间内通过重复检查确定均值和均值标准误差,并将其与受伤后的天数进行绘图。通过该图表,通过最小二乘法分析确定代表临床恢复率的线。对普通重症监护护士进行培训,使其能够独立对患者进行评分;发现他们的评定结果与主治医生检查得出的评分在统计学上一致。所呈现的数据突出了低氧血症对严重颅脑损伤神经学恢复速率的阻碍作用。这种用于定量评估颅脑损伤患者的简单临床分析方案允许评估各种治疗模式在改变恢复速率方面的疗效。