Samochowiec L, Wójciki J, Woyke M, Kadłubowska D, Jaworska M, Gawrońska-Szklarz B
Pol J Pharmacol Pharm. 1981 Mar-Apr;33(2):185-91.
Pigs received for 24 weeks a high-lipid diet containing cholesterol and coconut oil. Blood lipid fractions were assayed, electrophoretic separation of lipoproteids was carried out, and tests for blood coagulation parameters (fibrinogen content, partial thromboplastin time, paracoagulation test, blood platelets aggregation) were carried out. In the blood serum of experimental animals the content of triglycerides, cholesterol, free fatty acids, lipid phosphorous and beta-lipoproteids gradually increased. A hyperlipidemia corresponding to type IV of Fredrickson was obtained. No parallel changes in the results of studies on blood coagulation parameters were observed.
猪接受了为期24周的含胆固醇和椰子油的高脂饮食。检测了血脂成分，进行了脂蛋白的电泳分离，并进行了凝血参数（纤维蛋白原含量、部分凝血活酶时间、副凝血试验、血小板聚集）检测。实验动物血清中的甘油三酯、胆固醇、游离脂肪酸、脂质磷和β-脂蛋白含量逐渐增加。获得了符合弗雷德里克森IV型的高脂血症。在凝血参数研究结果中未观察到平行变化。
