Experimental atherosclerosis model in domestic pigs. Part II. Electrocardiographic and morphologic investigation.

Experimental atherosclerosis was produced in domestic pigs by administration for 24 weeks a high lipid diet containing cholesterol and coconut oil. ECG changes were not uniform: negative T, prolonged intraventricular conduction, and premature ventricular beats were observed. Macroscopic and microscopic anatomo-pathological studies revealed atheromatous changes in the aorta.