孕期及哺乳期使用普萘洛尔进行抗高血压治疗。
Anti-hypertensive therapy with propranolol during pregnancy and lactation.
作者信息
Taylor E A, Turner P
出版信息
Postgrad Med J. 1981 Jul;57(669):427-30. doi: 10.1136/pgmj.57.669.427.
Abstract
A hypertensive women was treated throughout pregnancy with propranolol 40 mg daily without complication. At delivery the umbilical cord plasma concentration was similar to that in the maternal venous plasma. Milk:plasma ratios were less than 1, although a higher ratio would be predicted. Estimated daily intake of propranolol in breast milk by the infant was about 3 micrograms. There appears to be no reason to advise women receiving propranolol to avoid breast feeding.
摘要
一位高血压女性在整个孕期每天服用40毫克普萘洛尔，未出现并发症。分娩时，脐带血浆浓度与母体静脉血浆浓度相似。母乳与血浆的比值小于1，尽管预计会有更高的比值。婴儿通过母乳摄入普萘洛尔的估计每日量约为3微克。似乎没有理由建议服用普萘洛尔的女性避免母乳喂养。
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Am J Obstet Gynecol. 1962 Aug 1;84:297-306. doi: 10.1016/0002-9378(62)90126-6.
2
Effects of adrenergic blocking agents and catecholamines in human pregnancy.肾上腺素能阻滞剂和儿茶酚胺在人类妊娠中的作用。
Am J Obstet Gynecol. 1968 Sep 15;102(2):226-35. doi: 10.1016/0002-9378(68)90323-2.
3
The effect of adrenergic receptor blocking drugs on the human uterus.肾上腺素能受体阻断药物对人体子宫的作用。
J Obstet Gynaecol Br Commonw. 1968 Feb;75(2):189-98. doi: 10.1111/j.1471-0528.1968.tb02031.x.
4
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The effect of propranolol on the onset of breathing at birth.普萘洛尔对出生时呼吸开始的影响。
Br J Anaesth. 1969 Sep;41(9):792.
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