Bott-Kanner G, Schweitzer A, Reisner S H, Joel-Cohen S J, Rosenfeld J B
Br J Obstet Gynaecol. 1980 Feb;87(2):110-4. doi: 10.1111/j.1471-0528.1980.tb04502.x.
A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies. Hydrallazine was continued through labour and delivery in all patients, while in eight patients propranolol was discontinued 2 to 15 days before delivery. Blood pressure control was uniformly good and superimposed pre-eclampsia did not occur during combined therapy. There were 14 livebirths and one unexplained stillbirth. Except for two cases of milk hypoglycemia, there were no neonatal complications.
在15次妊娠期间，对13例患有长期高血压的患者使用了普萘洛尔和肼屈嗪联合治疗。所有患者在分娩过程中均持续使用肼屈嗪，而8例患者在分娩前2至15天停用了普萘洛尔。联合治疗期间血压控制一直良好，未发生子痫前期。共分娩14例活产儿，1例原因不明的死产。除2例乳汁低血糖外，无新生儿并发症。
