Landau-Ferey J, George B, Benoit O
Rev Electroencephalogr Neurophysiol Clin. 1981 Sep;11(1):116-22. doi: 10.1016/s0370-4475(81)80042-1.
The waking periods during sleep of 16 patients, having been in post-traumatic coma for 5-40 days (aged 15-28 years), were studied electroencephalographically 1 month (T1) and 6 months (T6) after regaining consciousness and were compared with control subjects. The amount of waking (frequency and duration) increased appreciably at 1 month (20% of total sleep time and 21 awakenings per night) and was augmented even more in those cases in which the initial damage was more severe caudally and the duration of coma longer. At 6 months, the duration of waking was reduced somewhat (12% vs. 3% controls), but the frequency of awakening had not changed. By this stage the level of initial damage did not seem to produce any effect. These results show that the disturbance in the sleep-waking cycle regresses more rapidly the less severe the degree of initial damage was.
对16名曾处于创伤后昏迷5 - 40天（年龄在15 - 28岁）的患者在苏醒后1个月（T1）和6个月（T6）进行脑电图研究，观察其睡眠中的清醒期，并与对照组进行比较。清醒时间（频率和时长）在1个月时显著增加（占总睡眠时间的20%，每晚21次觉醒），在那些最初损伤更严重且昏迷持续时间更长的病例中增加得更多。在6个月时，清醒时长有所减少（与对照组相比为12%对3%），但觉醒频率没有变化。到这个阶段，最初损伤的程度似乎没有产生任何影响。这些结果表明，初始损伤程度越轻，睡眠 - 清醒周期的紊乱恢复得越快。
