Magnusson B, Björn-Rassmussen E, Hallberg L, Rossander L
Scand J Haematol. 1981 Sep;27(3):201-8.
The absorption from a 3 mg dose of ferrous iron was measured in 250 male subjects. The absorption was related to the log concentration of serum ferritin in 186 subjects of whom 99 were regular blood donors (r = -0.76), and to bone marrow haemosiderin grading in 52 subjects with varying iron status. The purpose was to try and establish a percentage absorption from such a dose that is representative of subjects who are borderline iron deficient. This information is necessary for food iron absorption studies in order (1) to calculate the absorption of iron from the diet at a given iron status and (2) compare the absorption of iron from different meals studied in different groups of subjects by different investigators. The results suggest that an absorption of about 40% of a 3 mg reference dose of ferrous iron is given in a fasting state, roughly corresponds to the absorption in borderline-iron-deficient subjects. The results indicate that this 40% absorption value corresponds to a serum ferritin level of 30 microgram/l and that food iron absorption in a group of subjects should be expressed preferably as the absorption corresponding to a reference-dose absorption of 40%, or possibly a serum ferritin level of 30 microgram/l.
在250名男性受试者中测量了3毫克剂量的亚铁的吸收情况。在186名受试者中，吸收情况与血清铁蛋白的对数浓度相关，其中99名是定期献血者（r = -0.76），在52名铁状态各异的受试者中，吸收情况与骨髓含铁血黄素分级相关。目的是试图确定这样一个剂量的吸收百分比，该百分比代表铁缺乏临界状态的受试者。这些信息对于食物铁吸收研究是必要的，以便（1）在给定的铁状态下计算饮食中铁的吸收量，以及（2）比较不同研究者在不同组受试者中研究的不同餐食中铁的吸收情况。结果表明，在禁食状态下，3毫克参考剂量的亚铁的吸收量约为40%，大致相当于铁缺乏临界状态受试者的吸收量。结果表明，这40%的吸收值对应于血清铁蛋白水平为30微克/升，并且一组受试者中的食物铁吸收情况最好表示为对应于40%参考剂量吸收的吸收量，或者可能是血清铁蛋白水平为30微克/升。
