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[瑞士两种常用结核菌素皮肤反应(曼托试验)的比较:诊断和流行病学意义]

[Comparison of skin reactions (Mantoux) made with 2 common tuberculins in Switzerland: diagnostic and epidemiologic implications].

作者信息

de Haller R

出版信息

Schweiz Med Wochenschr. 1981 Nov 14;111(46):1748-51.

PMID:7313644
Abstract

Simultaneous tuberculin skin tests (Mantoux) with the two products used in Switzerland (both from RT 23) were compared in 36 individuals. The results show a wide range of scatter with a very poor correlation coefficient. Out of these 36 subjects - of whom 12 had tuberculosis-with positive skin test with one tuberculin, only 11 had a positive result with the other, the mean diameter of the latter being 50% lower. These findings make interpretation of the national tuberculin cadaster hazardous and also render proper diagnosis in individual cases very difficult if the two tuberculins are used. As in other countries, only one tuberculin should be used on the national scale, in order to provide comparable epidemiological data and guarantee better individual diagnosis.

摘要

在36名个体中比较了瑞士使用的两种产品(均来自RT 23)同时进行的结核菌素皮肤试验(曼托试验)。结果显示分散度范围很广,相关系数非常低。在这36名受试者中,12人患有结核病,其中1人结核菌素皮肤试验呈阳性,只有11人另一种结核菌素试验呈阳性,后者的平均直径低50%。这些发现使得对国家结核菌素地籍的解释具有危险性,并且如果使用两种结核菌素,在个别病例中进行正确诊断也非常困难。与其他国家一样,在全国范围内应仅使用一种结核菌素,以便提供可比的流行病学数据并保证更好的个体诊断。

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