Lewis D J, Jakins P R
Thorax. 1981 Aug;36(8):622-4. doi: 10.1136/thx.36.8.622.
The ultrastructural appearance of rat tracheal submucosal glands after exposure to tobacco smoke for up to two years is described. Within the mucous cells many of the rough endoplasmic reticulum cisternae were grossly dilated with an accumulation of amorphous, electron-lucent material. The Golgi zones were prominent, and the secretion granules often contained dense cores, and appeared to have coalesced. Histochemically, increased amounts of sulphated mucus were present in exposed rats. Serous, ciliated, and myoepithelial cells were unaffected by smoke exposure.
描述了大鼠气管黏膜下腺暴露于烟草烟雾长达两年后的超微结构外观。在黏液细胞内，许多粗面内质网池明显扩张，积聚有无定形、电子透亮物质。高尔基体区域突出，分泌颗粒常含有致密核心，且似乎已经融合。组织化学分析显示，暴露的大鼠中硫酸化黏液的含量增加。浆液性、纤毛性和肌上皮细胞未受烟雾暴露的影响。
